Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ESRRG | P62508 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433557 | 0.90 | KDM4E (0.61) | POLBALDH1A1SMN1; SMN2ESRRGMEN1 | |
| SCHEMBL4459001 | 0.85 | POLB (0.53) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16935825 | 0.85 | POLB (0.53) | POLBALDH1A1SMN1; SMN2ESRRGMEN1 | |
| SCHEMBL5071492 | 0.85 | POLB (0.53) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2549950 | 0.85 | POLB (0.53) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6155598 | 0.85 | POLB (0.71) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13701835 | 0.83 | POLB (0.73) | POLBALDH1A1ESRRGTRPV1KDM4E | |
| SCHEMBL23346356 | 0.83 | TRPV1 (0.50) | POLBALDH1A1SMN1; SMN2ESRRGMEN1 | |
| SCHEMBL5072982 | 0.81 | POLB (0.58) | POLBSMN1; SMN2 | |
| SCHEMBL4475970 | 0.81 | KDM4E (0.51) | POLBALDH1A1SMN1; SMN2ESRRGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1997048674-A1 | DIARYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |