Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.63 |
| ▸ | FPR2 | P25090 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | FPR1 | P21462 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21001593 | 0.81 | KMT2A (0.76) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL21001592 | 0.81 | KMT2A (0.76) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL27703075 | 0.81 | KMT2A (0.71) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL19051485 | 0.80 | KMT2A (0.78) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL27846743 | 0.80 | KMT2A (0.74) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL31520097 | 0.80 | KMT2A (0.81) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL21001594 | 0.80 | KMT2A (0.81) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL27846742 | 0.80 | KMT2A (0.74) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL21001595 | 0.80 | KMT2A (0.81) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL3184939 | 0.79 | KMT2A (0.71) | KMT2AMEN1HCRTR1MAPTNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846942-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1998-12-08 | — | — | US | disclosed |