Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | EPOR | P19235 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491987 | 0.87 | EPOR (0.51) | CPB1CPB2LTA4HFOLH1EPOR | |
| SCHEMBL22804052 | 0.87 | EPOR (0.51) | CPB1CPB2LTA4HFOLH1EPOR | |
| SCHEMBL3776750 | 0.87 | EPOR (0.51) | CPB1CPB2LTA4HFOLH1EPOR | |
| SCHEMBL29517152 | 0.84 | FOLH1 (0.42) | MMP2CPB1CPB2ANPEPLTA4H | |
| SCHEMBL9574165 | 0.83 | EPOR (0.46) | FOLH1EPORTPSAB1TPSD1TPSG1 | |
| SCHEMBL4852056 | 0.83 | EPOR (0.46) | FOLH1EPORTPSAB1TPSD1TPSG1 | |
| SCHEMBL10477497 | 0.83 | EPOR (0.46) | FOLH1EPORTPSAB1TPSD1TPSG1 | |
| SCHEMBL3222447 | 0.82 | EPOR (0.52) | CPB1CPB2LTA4HFOLH1EPOR | |
| SCHEMBL16217828 | 0.81 | SIRT2 (0.55) | MMP2CPB1CPB2ANPEPLTA4H | |
| SCHEMBL19871881 | 0.81 | SIRT2 (0.55) | MMP2CPB1CPB2ANPEPLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834433-A | ANTITUMOR AND -CARCINOMA AGENTS; SMALL CELL LUNG AND PROSTATIC CARCINOMA; ANTIMIOTIC AND ANTISECRETORY AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0468497-A2 | Peptide-antagonists of bombesin/GRP | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |