Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.65 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906425 | 0.86 | CYP19A1 (0.62) | CYP19A1CYP26A1 | |
| SCHEMBL8697493 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP26A1CYP1A2CYP2C19 | |
| SCHEMBL9945342 | 0.79 | CYP19A1 (1.00) | CYP19A1CYP2C19 | |
| SCHEMBL3279272 | 0.79 | CYP19A1 (1.00) | CYP19A1CYP26A1CYP1A2CYP2C19 | |
| Tetrazole SCHEMBL1552742 | 0.76 | CYP19A1 (0.49) | CYP19A1CYP26A1 | |
| SCHEMBL8702461 | 0.72 | CYP19A1 (0.55) | CYP19A1CYP26A1 | |
| SCHEMBL28562505 | 0.72 | CYP19A1 (0.55) | CYP19A1CYP26A1 | |
| SCHEMBL29707706 | 0.72 | CYP19A1 (0.55) | CYP19A1CYP26A1 | |
| SCHEMBL8702184 | 0.69 | CYP19A1 (0.52) | CYP19A1CYP1A2 | |
| SCHEMBL8702187 | 0.69 | CYP19A1 (0.52) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |