Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700721 | 1.00 | EP300 (0.42) | EP300TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL8126261 | 0.83 | — | — | |
| SCHEMBL4130255 | 0.77 | EP300 (0.47) | EP300TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL4130257 | 0.77 | EP300 (0.47) | EP300TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL17240914 | 0.76 | EP300 (0.50) | EP300TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL29131352 | 0.76 | EP300 (0.45) | EP300TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL9262187 | 0.76 | EP300 (0.50) | EP300TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL14763494 | 0.76 | EP300 (0.45) | EP300TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL16431472 | 0.76 | EP300 (0.50) | EP300TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL6053797 | 0.76 | EP300 (0.50) | EP300TSHRKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |