Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769452 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL7385475 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL29543300 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL6769226 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL25896590 | 0.83 | CHRNA7 (0.44) | SMN1; SMN2CHRNA7MEN1KMT2AGBA1 | |
| SCHEMBL25896584 | 0.83 | CHRNA7 (0.44) | SMN1; SMN2CHRNA7MEN1KMT2AGBA1 | |
| SCHEMBL10941517 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL14574441 | 0.83 | CHRNA7 (0.44) | SMN1; SMN2CHRNA7MEN1KMT2AGBA1 | |
| SCHEMBL29299870 | 0.78 | MEN1 (0.41) | SMN1; SMN2CHRNA7MEN1KMT2AGBA1 | |
| SCHEMBL6739703 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2GAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789599-A | Aziridine compounds, methods of preparation and reactions thereof | DREXEL UNIVERSITY (US) | 1998-08-04 | — | — | US | disclosed |