Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8701425 | 1.00 | TDP1 (0.31) | TDP1LMNAKDM4EMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8701418 | 0.93 | TDP1 (0.32) | TDP1KDM4EMAPTHDAC1PTPN11 | |
| Trifluoroacetic Acid SCHEMBL8701863 | 0.91 | HDAC1 (0.31) | HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8701881 | 0.91 | HDAC1 (0.31) | HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8707941 | 0.89 | — | — | |
| Trifluoroacetic Acid SCHEMBL8705758 | 0.89 | HDAC1 (0.33) | HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8705789 | 0.89 | HDAC1 (0.33) | HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8707536 | 0.89 | HDAC1 (0.33) | TDP1LMNAKDM4EMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8707530 | 0.89 | HDAC1 (0.33) | TDP1LMNAKDM4EMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8701650 | 0.88 | HDAC1 (0.31) | TDP1KDM4EHDAC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838465-A1 | Pyridinium-substituted (lactamylvinyl)cephalosporin derivatives, their preparation and their use as antibiotics | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-29 | — | — | EP | disclosed |