Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GMNN | O75496 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | PTAFR | P25105 | 1/20 | 0.71 |
| ▸ | MTOR | P42345 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120138 | 0.91 | GMNN (0.62) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9120153 | 0.91 | GMNN (0.62) | GMNNUSP2LMNAPTAFRMTOR | |
| Iodide SCHEMBL9117195 | 0.90 | GMNN (0.61) | GMNNUSP2LMNAPTAFRMTOR | |
| Iodide SCHEMBL9117189 | 0.90 | GMNN (0.61) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL10506196 | 0.87 | GMNN (0.69) | GMNNUSP2LMNAPTAFRMTOR | |
| Hydrochloric Acid SCHEMBL9575824 | 0.86 | GMNN (0.68) | GMNNUSP2LMNAPTAFRMTOR | |
| Hydrochloric Acid SCHEMBL11064109 | 0.84 | GMNN (0.58) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL8538731 | 0.84 | GMNN (0.70) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL8701203 | 0.83 | GMNN (1.00) | GMNNUSP2LMNAPTAFRMTOR | |
| SCHEMBL9829818 | 0.80 | GMNN (0.51) | GMNNUSP2LMNAPTAFRMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836852-A1 | Use of amlexanox for the manufacture of a medicament for treating aphtous ulcers | CHEMEX/BLOCK DRUG, JV (US) | 1998-04-22 | — | — | EP | disclosed |