Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31470065 | 0.82 | HPGD (0.65) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL9266291 | 0.79 | HPGD (1.00) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7092018 | 0.77 | HPGD (0.56) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL6748042 | 0.73 | HPGD (0.69) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL6284450 | 0.73 | TDP1 (0.52) | HSPB1ALDH1A1L3MBTL1KMT2ANPC1 | |
| SCHEMBL11147387 | 0.73 | HPGD (0.64) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL11229678 | 0.72 | HPGD (0.55) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7416255 | 0.72 | HPGD (0.51) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2326248 | 0.72 | MAPT (0.64) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL9816756 | 0.72 | HPGD (0.58) | HPGDHSPB1ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840684-A | Glycopeptide antibiotic derivatives | ELI LILLY AND COMPANY (US) | 1998-11-24 | — | — | US | disclosed |