Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8701767 | 0.99 | SMN1; SMN2 (0.35) | SMN1; SMN2LMNATACR1CYP2D6DRD2 | |
| SCHEMBL8701074 | 0.92 | KMT2A (0.34) | SMN1; SMN2LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8701612 | 0.91 | KMT2A (0.33) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8701385 | 0.89 | TACR1 (0.45) | SMN1; SMN2LMNATACR1CYP2D6RAB9A | |
| SCHEMBL8703803 | 0.86 | TACR1 (0.36) | LMNATACR1CYP2D6DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8701130 | 0.85 | TACR1 (0.35) | LMNATACR1CYP2D6DRD2DRD3 | |
| SCHEMBL8701541 | 0.85 | TACR1 (0.38) | SMN1; SMN2TACR1DRD2DRD3POLB | |
| SCHEMBL8701299 | 0.83 | TACR1 (0.36) | TACR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8702143 | 0.82 | TACR1 (0.35) | TACR1MEN1KMT2A | |
| SCHEMBL8705094 | 0.82 | TACR1 (0.35) | LMNATACR1CYP2D6TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | claimed |
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | disclosed |