Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.69 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529895 | 1.00 | HRH1 (0.69) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| SCHEMBL29145039 | 1.00 | HRH1 (0.69) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| SCHEMBL28342947 | 1.00 | HRH1 (0.69) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| SCHEMBL28446806 | 1.00 | HRH1 (0.69) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| SCHEMBL31591272 | 1.00 | HRH1 (0.69) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| SCHEMBL28566857 | 1.00 | HRH1 (0.69) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| Water SCHEMBL28352691 | 0.98 | HRH1 (0.67) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| SCHEMBL26416035 | 0.98 | HRH1 (0.66) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28007909 | 0.96 | HRH1 (0.63) | HRH1NAAACYP1A2HRH3SMN1; SMN2 | |
| SCHEMBL3046123 | 0.91 | HRH1 (0.62) | HRH1NAAACYP1A2HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116946989-A | Preparation method of phosphane/deuterated phosphane and derivatives thereof | 北京大学 | 2023-10-27 | — | — | CN | disclosed |
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1997048674-A1 | DIARYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |
| EP-0299379-B1 | PENTADIENAMIDE PAF-ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4927838-A | CARDIOVASCULAR DISORDERS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4927826-A | Cycloproylpropenamides useful as platelet activing factor (PAF) antagonists | HOFFMAN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4916145-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1990-04-10 | — | — | US | disclosed |
| EP-0299379-A1 | Pentadienamide PAF-antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4786646-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-22 | — | — | US | disclosed |