Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP10 | P09238 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077495 | 0.89 | MEN1 (0.48) | MEN1KMT2ATRPM8IDO1ACP3 | |
| SCHEMBL2303442 | 0.84 | KMT2A (0.49) | MEN1KMT2AIDO1ACP3CASR | |
| SCHEMBL28361247 | 0.82 | KMT2A (0.49) | MEN1KMT2AIDO1ACP3CASR | |
| SCHEMBL28211972 | 0.82 | EPHX1 (0.59) | EPHX1 | |
| SCHEMBL31607867 | 0.82 | F7 (0.44) | IDO1EPHX1PARP1 | |
| SCHEMBL26448016 | 0.82 | F7 (0.44) | IDO1EPHX1PARP1 | |
| SCHEMBL20425537 | 0.81 | KMT2A (0.46) | MEN1KMT2AIDO1ACP3CASR | |
| SCHEMBL28419253 | 0.81 | CYP2C9 (0.49) | MEN1KMT2AEPHX1 | |
| SCHEMBL30075866 | 0.80 | MEN1 (0.50) | MEN1KMT2ATRPM8ACP3EPHX1 | |
| SCHEMBL27451392 | 0.80 | MEN1 (0.50) | MEN1KMT2ATRPM8ACP3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |