Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8707078 | 0.99 | NPSR1 (0.38) | NPSR1HTTL3MBTL1CA12CA9 | |
| SCHEMBL8708216 | 0.91 | MCOLN3 (0.44) | NPSR1HTTL3MBTL1CA12CA9 | |
| Hydrochloric Acid SCHEMBL8702401 | 0.90 | MCOLN3 (0.44) | NPSR1HTTL3MBTL1CA12CA9 | |
| SCHEMBL8701299 | 0.88 | TACR1 (0.36) | L3MBTL1ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8702143 | 0.87 | TACR1 (0.35) | L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8706539 | 0.85 | KMT2A (0.32) | ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8701563 | 0.84 | KMT2A (0.32) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8701074 | 0.83 | KMT2A (0.34) | HTTALDH1A1LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8701612 | 0.82 | KMT2A (0.33) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8703684 | 0.82 | POLB (0.49) | HTTL3MBTL1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | claimed |