Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 4/20 | 0.51 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610612 | 0.86 | FOLH1 (0.60) | MMENPC1RAB9AFOLH1 | |
| SCHEMBL6343393 | 0.86 | FOLH1 (0.60) | MMENPC1RAB9AFOLH1 | |
| SCHEMBL5507066 | 0.83 | NPC1 (0.49) | MMENPC1RAB9AFOLH1SMN1; SMN2 | |
| SCHEMBL6130477 | 0.83 | MME (0.51) | MMENPC1RAB9APPARGGPR132 | |
| SCHEMBL7004556 | 0.83 | NPC1 (0.49) | MMENPC1RAB9AFOLH1SMN1; SMN2 | |
| SCHEMBL5507068 | 0.83 | NPC1 (0.49) | MMENPC1RAB9AFOLH1SMN1; SMN2 | |
| SCHEMBL6130478 | 0.83 | MME (0.51) | MMENPC1RAB9APPARGGPR132 | |
| SCHEMBL7211707 | 0.83 | MME (0.51) | MMENPC1RAB9APPARGGPR132 | |
| SCHEMBL6158695 | 0.83 | CA1 (0.59) | MMEACECTSLCNR2TSHR | |
| SCHEMBL6158692 | 0.83 | CA1 (0.59) | MMEACECTSLCNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |