Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 11/20 | 0.51 |
| ▸ | CTSL | P07711 | 6/20 | 0.51 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312774 | 0.77 | CAPN1 (0.69) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL7312791 | 0.77 | CAPN1 (0.69) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL6828190 | 0.77 | CAPN1 (0.72) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL7327426 | 0.77 | CAPN1 (0.78) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL9828791 | 0.77 | CAPN1 (0.78) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL27809377 | 0.77 | CAPN1 (0.78) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL7300366 | 0.76 | CAPN1 (0.60) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL7315481 | 0.76 | CAPN1 (0.70) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL7315453 | 0.76 | CAPN1 (0.70) | CAPN1CTSKCTSLHTRA1CTSS | |
| SCHEMBL20825246 | 0.76 | CAPN1 (0.78) | CAPN1CTSKCTSLHTRA1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871454-A4 | — | — | 1998-11-25 | — | — | EP | disclosed |
| EP-0871454-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997003679-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-02-06 | — | — | WO | disclosed |