Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707616 | 1.00 | ABCB1 (0.62) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8703165 | 1.00 | ABCB1 (0.62) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL8710531 | 0.99 | ABCB1 (0.61) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL8703553 | 0.99 | ABCB1 (0.61) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL8703558 | 0.99 | ABCB1 (0.61) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8703946 | 0.94 | ABCB1 (0.57) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8703339 | 0.93 | ABCB1 (0.56) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8703273 | 0.93 | ABCB1 (0.56) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL8702858 | 0.93 | ABCB1 (0.56) | ABCB1DRD2HTR1ATP53CYP3A4 | |
| SCHEMBL8703510 | 0.89 | ABCB1 (0.50) | ABCB1DRD2HTR1ATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844000-A1 | Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis | SANKYO COMPANY LIMITED (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |