SCHEMBL870441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870442	1.00	PDE4B (0.49)	PDE4BCNR2PDE4APDE4CPDE4D
	SCHEMBL3011847	0.96	PDE4B (0.50)	PDE4BHPGDS
	SCHEMBL870870	0.96	PDE4B (0.50)	PDE4BHPGDS
	SCHEMBL871840	0.94	PDE4B (0.47)	PDE4BCNR2PDE4APDE4CPDE4D
	SCHEMBL871841	0.94	PDE4B (0.47)	PDE4BCNR2PDE4APDE4CPDE4D
	SCHEMBL871933	0.94	PDE4B (0.48)	PDE4BCNR2PDE4APDE4CPDE4D
	SCHEMBL871934	0.94	PDE4B (0.48)	PDE4BCNR2PDE4APDE4CPDE4D
	SCHEMBL871748	0.93	PDE4B (0.54)	PDE4BCNR2HPGDSCNR1
	SCHEMBL871749	0.93	PDE4B (0.54)	PDE4BCNR2HPGDSCNR1
	SCHEMBL871868	0.92	PDE4B (0.49)	PDE4BCNR2PDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.