Hexane

Hexane

SCHEMBL8705498

CCCCCC.CCCCCC.CCCCCC.CCCCCC

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.88
THRB P10828 1/20 0.88
LMNA P02545 3/20 0.75
SLC22A1 O15245 3/20 0.58
SLC22A2 O15244 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
DNM1 Q05193 5/20 0.54
ALDH1A1 P00352 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
HSD17B10 Q99714 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL9557662 1.00 TSHR (0.88) TSHRTHRBLMNASLC22A1SLC22A2
Hexane SCHEMBL357364 1.00 TSHR (0.88) TSHRTHRBLMNASLC22A1SLC22A2
Hexane SCHEMBL5017645 1.00 TSHR (0.88) TSHRTHRBLMNASLC22A1SLC22A2
Hexane SCHEMBL11650566 1.00 TSHR (0.88) TSHRTHRBLMNASLC22A1SLC22A2
Hexane SCHEMBL399 1.00
Hexane SCHEMBL8151140 1.00 TSHR (0.88) TSHRTHRBLMNASLC22A1SLC22A2
Hexane SCHEMBL9859565 1.00 TSHR (0.88) TSHRTHRBLMNASLC22A1SLC22A2
Tetradecane SCHEMBL25387874 0.94 TSHR (1.00) TSHRTHRBLMNASLC22A1DNM1
Decane SCHEMBL23499900 0.94 TSHR (1.00) TSHRTHRBLMNASLC22A1DNM1
Hexane SCHEMBL23175213 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100378054-C Preparation method of 3, 3-dimethylbutyraldehyde NUTRASWEET CO (US) 2008-04-02 CN disclosed
US-5834571-A PROVIDING AT LEAST ONE LIQUID IN POLYMERIZATION ZONE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-11-10 US disclosed
US-4977291-A CATALYTIC HYDROGENATION OF CORRESPONDING AROMATIC CONTAINING COMPOUND ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1990-12-11 US disclosed
US-4405769-A TRANSITION METAL AND METALLIC HALIDE COMPOUND WITH PRECIPITATING HALIDE COMPOUND CAPSHEW CHARLES E (US) 1983-09-20 US disclosed