Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Endrin SCHEMBL10671688 | 1.00 | CYP3A4 (0.77) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Endrin SCHEMBL9751494 | 0.88 | CYP3A4 (0.60) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Endrin SCHEMBL26100507 | 0.88 | CYP3A4 (1.00) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Endrin SCHEMBL22946184 | 0.88 | CYP3A4 (1.00) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Endrin SCHEMBL72828 | 0.88 | CYP3A4 (1.00) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Endrin SCHEMBL10414610 | 0.88 | CYP3A4 (1.00) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Endrin SCHEMBL20885948 | 0.88 | CYP3A4 (1.00) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Endrin SCHEMBL21820798 | 0.88 | CYP3A4 (1.00) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Dieldrin SCHEMBL72829 | 0.88 | CYP3A4 (1.00) | CYP3A4TSHRMAPK14MAPTLMNA | |
| Dieldrin SCHEMBL29549662 | 0.86 | CYP3A4 (0.96) | CYP3A4TSHRMAPK14MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729351-A4 | VESICLES WITH CONTROLLED RELEASE OF ACTIVES | DEPOTECH CORP (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0729351-A1 | VESICLES WITH CONTROLLED RELEASE OF ACTIVES | DEPOTECH CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995013796-A1 | VESICLES WITH CONTROLLED RELEASE OF ACTIVES | DEPOTECH CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |
| US-5209604-A | Soil decontamination | SHELL OIL COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-4919819-A | ADSORPTION FROM AQUEOUS SLURRY ONTO REHYDRATABLE ALUMINA, FILTRATION; REGENERATING ALUMINA BY HEATING | GEM, INC. (US) | 1990-04-24 | — | — | US | disclosed |