SCHEMBL8707233

SCHEMBL8707233

c1ccc(CNCC2CCN(Cc3ccccc3)CC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 11/20 1.00
HDAC3 O15379 1/20 0.74
HDAC4 P56524 1/20 0.74
HDAC1 Q13547 1/20 0.74
HDAC7 Q8WUI4 1/20 0.74
HDAC2 Q92769 1/20 0.74
HDAC10 Q969S8 1/20 0.74
HDAC11 Q96DB2 1/20 0.74
HDAC8 Q9BY41 1/20 0.74
HDAC6 Q9UBN7 1/20 0.74
HDAC9 Q9UKV0 1/20 0.74
HDAC5 Q9UQL6 1/20 0.74
CCR3 P51677 1/20 0.63
BCHE P06276 1/20 0.62
ACHE P22303 1/20 0.62
BACE1 P56817 1/20 0.62
MAN2A1 Q16706 1/20 0.60
MAN1B1 Q9UKM7 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28651928 0.86 HDAC6 (1.00) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL8406869 0.86 CXCR4 (0.75) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL6215695 0.85 CXCR4 (0.74) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL28657592 0.85 HDAC3 (0.73) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL16083006 0.82 CXCR4 (0.69) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL2934330 0.82 CXCR4 (0.69) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL15663120 0.82 CXCR4 (0.69) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL5723679 0.81 CXCR4 (0.68) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL28169202 0.81 CXCR4 (0.68) CXCR4HDAC3HDAC4HDAC1HDAC7
SCHEMBL5803190 0.80 CXCR4 (0.66) CXCR4HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5849732-A Phenol compound having antioxidative activity and the process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1998-12-15 US disclosed
EP-0790240-A1 Phenol-derivatives having pharmaceutical activity and process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1997-08-20 EP disclosed