SCHEMBL8707386

SCHEMBL8707386

COC1CC(C(=O)O)(C(=O)Cc2c(C)cc(C)cc2C)CC1OC

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
P2RX7 Q99572 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8710264 0.85 MEN1 (0.32) P2RX7
SCHEMBL8708077 0.84 HPGD (0.36) MAPTKDM4EPOLBP2RX7
SCHEMBL8704132 0.84 KDM4E (0.33) MAPTKDM4EPOLBP2RX7
SCHEMBL8704649 0.83 POLB (0.32) MAPTKDM4EPOLB
SCHEMBL8708079 0.81 DPP4 (0.33) MAPTKDM4EPOLBP2RX7
SCHEMBL8704709 0.81 POLB (0.33) MAPTKDM4EPOLB
SCHEMBL8703838 0.78 KDM4E (0.35) MAPTKDM4EPOLB
SCHEMBL8708170 0.77 KDM4E (0.35) MAPTKDM4EPOLBP2RX7
SCHEMBL8707216 0.77 HRH3 (0.34) MAPTKDM4EPOLBP2RX7
SCHEMBL8703671 0.77 POLB (0.34) MAPTKDM4EPOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5808135-A HERBICIDE; PESTICIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed