Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159768 | 0.80 | POLB (0.40) | POLBLMNASMN1; SMN2NTRK1PIM1 | |
| SCHEMBL1058104 | 0.78 | HTT (0.39) | POLBLMNASMN1; SMN2NTRK1PIM1 | |
| SCHEMBL4793593 | 0.77 | POLB (0.38) | POLBLMNASMN1; SMN2NTRK1PIM1 | |
| SCHEMBL6258938 | 0.77 | POLB (0.55) | POLBLMNASMN1; SMN2NTRK1PIM1 | |
| SCHEMBL28846830 | 0.77 | POLB (0.38) | POLBLMNASMN1; SMN2NTRK1PIM1 | |
| SCHEMBL27592637 | 0.73 | TYK2 (0.38) | POLBCDC7CASP1 | |
| SCHEMBL28143127 | 0.72 | CDC7 (0.46) | LMNASMN1; SMN2NTRK1PIM1CDC7 | |
| SCHEMBL27560680 | 0.70 | HTR2B (0.42) | SMN1; SMN2CDC7HPGDTSHR | |
| SCHEMBL2546883 | 0.70 | POLB (0.45) | POLBLMNASMN1; SMN2NTRK1PIM1 | |
| SCHEMBL30377092 | 0.69 | HSD17B10 (0.43) | POLBNTRK1PIM1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5734060-A | Method of preparing acylisocyanates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1998-03-31 | — | — | US | disclosed |