SCHEMBL8708019

SCHEMBL8708019

COC(=O)C1CC(O)C(O)CC1C(=O)Cc1c(C)cc(C)cc1C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP2C19 P33261 2/20 0.35
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8709256 0.89 KDM4E (0.40) CYP1A2HSD17B10CYP3A4CYP2D6TSHR
SCHEMBL8709716 0.89 KDM4E (0.35) CYP1A2HSD17B10CYP3A4CYP2D6TSHR
SCHEMBL8703827 0.88 KCNQ3 (0.37) CYP1A2HSD17B10CYP3A4CYP2D6TSHR
SCHEMBL8703643 0.87 MAPT (0.34) CYP1A2HSD17B10CYP3A4CYP2D6TSHR
SCHEMBL8709035 0.87 CA1 (0.37) CYP1A2HSD17B10TSHRMAPK1CYP2C19
SCHEMBL8703672 0.87 CYP3A4 (0.32) CYP1A2HSD17B10CYP3A4CYP2D6TSHR
SCHEMBL10199936 0.86 CYP1A2 (0.36) CYP1A2HSD17B10CYP3A4CYP2D6TSHR
SCHEMBL8021762 0.85 CA1 (0.42) TSHRMAPT
SCHEMBL8710228 0.85 KDM4E (0.33) ALDH1A1MAPT
SCHEMBL8703058 0.84 MAPT (0.31) TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5808135-A HERBICIDE; PESTICIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed