SCHEMBL8709206

SCHEMBL8709206

CC(OCOCN1CNc2c1nc(N)[nH]c2=O)P(=O)(O)O.[NaH]

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 16/20 0.59
PNP P00491 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8708938 0.99 HPRT1 (0.60) HPRT1PNP
SCHEMBL9056240 0.84 HPRT1 (0.71) HPRT1
SCHEMBL8899140 0.84 HPRT1 (0.74) HPRT1PNP
SCHEMBL8896319 0.81 HPRT1 (0.68) HPRT1PNP
SCHEMBL6270124 0.80 HPRT1 (0.60) HPRT1PNP
Phosphoric Acid SCHEMBL11313332 0.80 HPRT1 (0.64) HPRT1PNP
SCHEMBL2775722 0.79 HPRT1 (0.55) HPRT1
SCHEMBL9538076 0.79 HPRT1 (0.71) HPRT1PNP
Phosphoric Acid SCHEMBL6439956 0.78 HPRT1 (0.65) HPRT1PNP
Phosphoric Acid SCHEMBL11308939 0.78 HPRT1 (0.65) HPRT1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726174-A VIRICIDES, ANTITUMOR AGENTS INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1998-03-10 US disclosed
US-5696265-A ANTIRETROVIRAL; ANTITUNOR AGENT INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1997-12-09 US disclosed
US-5693798-A ACTIVE AGAINST RETROVIRAL DISEASES; PROPHYLAXIS INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1997-12-02 US disclosed
US-5688778-A VIRICIDES INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1997-11-18 US disclosed
US-5686611-A Nucleoside analogs INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1997-11-11 US disclosed
EP-0398231-B1 Nucleoside analogs ACAD OF SCIENCE CZECH REPUBLIC (CZ) 1997-07-16 EP disclosed
EP-0398231-A2 Nucleoside analogs INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1990-11-22 EP disclosed