Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.45 |
| ▸ | WNT3A | P56704 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631350 | 0.84 | CTNNB1 (0.46) | CTNNB1WNT3ACYP2A6PTPRCPTPN6 | |
| SCHEMBL9087585 | 0.84 | CTNNB1 (0.40) | CTNNB1WNT3ACYP2A6BLMNPSR1 | |
| SCHEMBL9087590 | 0.84 | CTNNB1 (0.40) | CTNNB1WNT3ACYP2A6BLMNPSR1 | |
| SCHEMBL26619325 | 0.83 | AKR1C3 (0.53) | CTNNB1WNT3ALMNATSHRKDM4E | |
| SCHEMBL11190893 | 0.80 | AKR1C3 (0.53) | CTNNB1WNT3ACYP2A6TSHRPTPRC | |
| SCHEMBL12473739 | 0.78 | CYP2A6 (0.42) | CTNNB1WNT3ACYP2A6PTPRCPTPN6 | |
| SCHEMBL12653206 | 0.78 | CTNNB1 (0.41) | CTNNB1WNT3ACYP2A6PTPRCPTPN6 | |
| SCHEMBL27706823 | 0.77 | CYP2A6 (0.43) | CTNNB1WNT3ACYP2A6PTPRCPTPN6 | |
| SCHEMBL19405853 | 0.77 | UGT2B7 (0.50) | CTNNB1WNT3ACYP2A6PTPRCPTPN6 | |
| SCHEMBL28159357 | 0.77 | CYP2A6 (0.43) | CTNNB1WNT3ACYP2A6PTPRCPTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043967-A1 | PROCESS FOR PRODUCING 2-(BENZO[b]THIOPHEN-5-YL)-2-HYDROXYACETIC ACID DERIVATIVES, OPTICALLY ACTIVE COMPOUNDS THEREOF, OR SALTS OF BOTH | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| EP-0565965-B1 | Benzo b thiophen-5-yl derivative and process for producing the same | TOYAMA CHEMICAL CO LTD (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-5380878-A | Benzo[b]thiophen-5-yl derivative and process for producing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0565965-A2 | Benzo b thiophen-5-yl derivative and process for producing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |