Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710196 | 1.00 | ADRB3 (0.70) | ADRB3ADRB1ADRB2MTNR1AMTNR1B | |
| SCHEMBL8999624 | 0.94 | ADRB3 (0.72) | ADRB3ADRB1ADRB2MTNR1AMTNR1B | |
| SCHEMBL8710046 | 0.91 | ADRB3 (0.71) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8710317 | 0.91 | ADRB3 (0.71) | ADRB3ADRB1ADRB2 | |
| SCHEMBL1812921 | 0.89 | ADRB3 (0.56) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8710122 | 0.89 | ADRB3 (0.73) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8709968 | 0.89 | ADRB3 (0.73) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7572357 | 0.87 | ADRB3 (0.69) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8710830 | 0.86 | ADRB3 (0.71) | ADRB3ADRB1ADRB2 | |
| SCHEMBL678590 | 0.86 | ADRB3 (0.71) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817689-A | ADRENERGIC RECEPTOR-STIMULATING AGENT, OBESITY, DIABETES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |