Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615518 | 0.89 | AR (0.69) | ARKCNH2SRD5A2 | |
| SCHEMBL7615525 | 0.89 | AR (0.69) | ARKCNH2SRD5A2 | |
| SCHEMBL5339929 | 0.80 | AR (0.58) | ARKCNH2SRD5A2 | |
| SCHEMBL5247468 | 0.80 | AR (0.58) | ARKCNH2SRD5A2 | |
| SCHEMBL5341211 | 0.80 | AR (0.55) | ARKCNH2SRD5A2 | |
| SCHEMBL5242813 | 0.80 | AR (0.55) | ARKCNH2SRD5A2 | |
| SCHEMBL13403560 | 0.79 | AR (0.56) | ARKCNH2SRD5A2 | |
| SCHEMBL14336866 | 0.79 | AR (0.53) | ARKCNH2SRD5A2 | |
| SCHEMBL5217723 | 0.76 | SRD5A2 (0.62) | ARKCNH2SRD5A2 | |
| SCHEMBL20368986 | 0.76 | SRD5A2 (0.62) | ARSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880540-A1 | 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE | HOECHST MARION ROUSSEL, INC. (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997030069-A1 | 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-08-21 | — | — | WO | disclosed |