SCHEMBL8710150

SCHEMBL8710150

C=CC(=O)OCC(C)CC(C)(C)C

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.60
ALDH1A1 P00352 4/20 0.40
TP53 P04637 3/20 0.40
HIF1A Q16665 3/20 0.40
CYP3A4 P08684 2/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.39
THRB P10828 2/20 0.38
EGFR P00533 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18759757 0.86 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11750771 0.85 TSHR (0.39) TSHRALDH1A1HPGDEGFR
SCHEMBL11750414 0.85 TSHR (0.39) TSHRALDH1A1HPGDEGFR
SCHEMBL7518621 0.84 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8965855 0.84 TSHR (0.75) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL231256 0.82 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7726585 0.81 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6678990 0.80 TSHR (0.69) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL31059272 0.80 TSHR (0.69) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL26996591 0.80 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO claimed
US-5830385-A DISPERSED IN PHOTOPOLYMERIZABLE MATRIX MATERIAL RAYCHEM CORPORATION (US) 1998-11-03 US claimed
EP-0799287-A1 METHOD OF MAKING LIQUID CRYSTAL COMPOSITE RAYCHEM CORPORATION (US) 1997-10-08 EP claimed
WO-1996019547-A1 METHOD OF MAKING LIQUID CRYSTAL COMPOSITE RAYCHEM CORPORATION (US) 1996-06-27 WO claimed
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO disclosed
US-4048130-A COPOLYMERIZATION, UNSATURATED ACIDS LONZA LTD. (CH) 1977-09-13 US disclosed