⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyruvate SCHEMBL1750 | 1.00 | — | — | |
| Pyruvate SCHEMBL13165964 | 1.00 | — | — | |
| Pyruvate SCHEMBL300872 | 1.00 | — | — | |
| Pyruvate SCHEMBL30036647 | 1.00 | — | — | |
| Pyruvate SCHEMBL8710301 | 1.00 | TSHR (0.60) | — | |
| Pyruvate SCHEMBL274319 | 1.00 | TSHR (0.60) | — | |
| Pyruvate SCHEMBL23829857 | 1.00 | — | — | |
| Pyruvate SCHEMBL29358755 | 1.00 | — | — | |
| Pyruvate SCHEMBL1331078 | 1.00 | — | — | |
| Pyruvate SCHEMBL10425930 | 1.00 | TSHR (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153023-B | The synthetic method of 2 amino, 4 bromopyridine | 成都同创源医药科技有限公司 | 2018-04-13 | — | — | CN | claimed |
| US-11839213-B2 | Antimicrobial, disinfecting, and wound healing compositions and methods for producing and using the same | Armis Biopharma, Inc. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210337794-A1 | ANTIMICROBIAL, DISINFECTING, AND WOUND HEALING COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME | Armis Biopharma, Inc. | 2021-11-04 | — | — | US | disclosed |
| US-11006629-B2 | Antimicrobial, disinfecting, and wound healing compositions and methods for producing and using the same | Armis Biopharma, Inc. (US) | 2021-05-18 | — | — | US | disclosed |
| CN-105153023-B | The synthetic method of 2 amino, 4 bromopyridine | 成都同创源医药科技有限公司 | 2018-04-13 | — | — | CN | disclosed |
| US-20170303538-A1 | ANTIMICROBIAL, DISINFECTING, AND WOUND HEALING COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME | Armis Biopharma, Inc. | 2017-10-26 | — | — | US | disclosed |
| US-5714515-A | Pharmaceutical alpha-keto carboxylic acid compositions, method of making and use thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1998-02-03 | — | — | US | disclosed |
| WO-1997041848-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ALPHA-KETO CARBOXYLATES | THE GOVERNMENT OF THE UNITED STATES, REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1997-11-13 | — | — | WO | disclosed |
| US-5536751-A | PHOSPHORYLATION POTENTIAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1996-07-16 | — | — | US | disclosed |