Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702531 | 0.98 | HAO1 (0.53) | KDM1ALTA4HTSHRHAO1STAT3 | |
| SCHEMBL26154062 | 0.96 | KDM1A (0.53) | KDM1ALTA4HTSHRHAO1STAT3 | |
| SCHEMBL19322267 | 0.91 | KDM1A (0.57) | KDM1ALTA4HTSHRMMP3SLC6A2 | |
| SCHEMBL3970721 | 0.91 | KDM1A (0.57) | KDM1ALTA4HTSHRMMP3SLC6A2 | |
| SCHEMBL6704196 | 0.89 | HAO1 (0.59) | HAO1STAT3MAPTALOX12SMN1; SMN2 | |
| Glycolic Acid SCHEMBL2762978 | 0.85 | STAT3 (0.52) | HAO1STAT3MMP3 | |
| SCHEMBL20011398 | 0.83 | KDM1A (0.42) | KDM1ALTA4HHAO1STAT3MMP3 | |
| SCHEMBL24161870 | 0.82 | ESR2 (0.53) | KDM1ALTA4HTSHRMMP3SLC6A2 | |
| SCHEMBL9391575 | 0.82 | CETP (0.50) | LTA4HTSHRMAPT | |
| SCHEMBL949252 | 0.82 | SLC18A3 (0.68) | KDM1ALTA4HSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720598-B1 | PHENOXYPHENYL CYCLOPENTENYL HYDROXYUREAS | PFIZER (US) | 1998-10-07 | — | — | EP | disclosed |
| US-5792882-A | Phenoxyphenyl cyclopentenyl hydroxyureas | PFIZER INC. (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0720598-A1 | PHENOXYPHENYL CYCLOPENTENYL HYDROXYUREAS | PFIZER INC. (US) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995005360-A1 | PHENOXYPHENYL CYCLOPENTENYL HYDROXYUREAS | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |