Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL10623601 | 0.85 | TSHR (0.41) | KCNN4LMNACYP2D6TSHRATM | |
| SCHEMBL55166 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL11519580 | 0.79 | TSHR (0.37) | LMNATSHRHTR6 | |
| SCHEMBL4517726 | 0.79 | TSHR (0.37) | LMNATSHRHTR6 | |
| Fluoride SCHEMBL27669402 | 0.79 | TSHR (0.37) | LMNATSHRHTR6 | |
| SCHEMBL14875991 | 0.79 | TSHR (0.37) | LMNATSHRHTR6 | |
| SCHEMBL2799322 | 0.79 | TSHR (0.37) | LMNATSHRHTR6 | |
| Hydrochloric Acid SCHEMBL11803910 | 0.79 | TSHR (0.37) | LMNATSHRHTR6KDM4ECYP3A4 | |
| SCHEMBL16286660 | 0.79 | TSHR (0.37) | LMNATSHRHTR6 | |
| SCHEMBL27876203 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856014-A1 | SUPPORTED CATALYST COMPONENT, SUPPORTED CATALYST, PREPARATION PROCESS, POLYMERIZATION PROCESS, COMPLEX COMPOUNDS, AND THEIR PREPARATION | THE DOW CHEMICAL COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1996028480-A1 | SUPPORTED CATALYST COMPONENT, SUPPORTED CATALYST, PREPARATION PROCESS, POLYMERIZATION PROCESS, COMPLEX COMPOUNDS, AND THEIR PREPARATION | THE DOW CHEMICAL COMPANY (US) | 1996-09-19 | — | — | WO | disclosed |