Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716567 | 0.96 | MEN1 (0.56) | MEN1KMT2AHTR1FLMNASMN1; SMN2 | |
| Fumaric Acid SCHEMBL9233858 | 0.96 | MEN1 (0.51) | MEN1KMT2AHTR1FLMNASMN1; SMN2 | |
| Fumaric Acid SCHEMBL9233869 | 0.96 | MEN1 (0.51) | MEN1KMT2AHTR1FLMNASMN1; SMN2 | |
| Fumaric Acid SCHEMBL8712490 | 0.93 | MEN1 (0.51) | MEN1KMT2AHTR1FLMNASMN1; SMN2 | |
| Fumaric Acid SCHEMBL8712491 | 0.93 | MEN1 (0.51) | MEN1KMT2AHTR1FLMNASMN1; SMN2 | |
| SCHEMBL8711150 | 0.93 | MEN1 (0.53) | MEN1KMT2AHTR1FLMNASMN1; SMN2 | |
| SCHEMBL8711420 | 0.91 | SMN1; SMN2 (0.56) | MEN1KMT2ALMNASMN1; SMN2ACHE | |
| Fumaric Acid SCHEMBL9230021 | 0.91 | MEN1 (0.49) | MEN1KMT2AHTR1FLMNASMN1; SMN2 | |
| Fumaric Acid SCHEMBL9230029 | 0.91 | MEN1 (0.49) | MEN1KMT2AHTR1FLMNASMN1; SMN2 | |
| SCHEMBL8710697 | 0.90 | SMN1; SMN2 (0.51) | MEN1KMT2AHTR1FLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |