SCHEMBL8712239

SCHEMBL8712239

Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc([O])cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.76
CA1 P00915 3/20 0.76
CA2 P00918 3/20 0.76
CA9 Q16790 3/20 0.76
CA4 P22748 2/20 0.76
CA6 P23280 2/20 0.76
CA5A P35218 2/20 0.76
CA7 P43166 2/20 0.76
CA13 Q8N1Q1 2/20 0.76
CA14 Q9ULX7 2/20 0.76
TP53 P04637 1/20 0.76
LMNA P02545 3/20 0.75
PPARG P37231 1/20 0.72
RAB9A P51151 1/20 0.72
RXFP1 Q9HBX9 1/20 0.72
NR2E3 Q9Y5X4 1/20 0.72
NCOR2 Q9Y618 1/20 0.72
KMT2A Q03164 5/20 0.66
MEN1 O00255 4/20 0.66
USP2 O75604 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1928662 0.94 CA12 (0.85) CA12CA1CA2CA9CA4
SCHEMBL6243996 0.94 CA12 (0.85) CA12CA1CA2CA9CA4
SCHEMBL1395600 0.89 CA12 (0.78) CA12CA1CA2CA9CA4
SCHEMBL5187415 0.88 CA12 (0.76) CA12CA1CA2CA9CA4
SCHEMBL20568276 0.88 CA12 (0.76) CA12CA1CA2CA9CA4
SCHEMBL6470672 0.88 CA12 (0.76) CA12CA1CA2CA9CA4
SCHEMBL9486513 0.86 CA12 (0.74) CA12CA1CA2CA9CA4
Ly-181984 SCHEMBL4612056 0.86 RECQL (0.74) CA12CA1CA2CA9CA4
SCHEMBL9489786 0.86 KMT2A (0.74) CA12CA1CA2CA9CA4
SCHEMBL29973557 0.86 CA1 (1.00) CA12CA1CA2CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5851951-A Heat sensitive recording material OJI PAPER CO., LTD. (JP) 1998-12-22 US disclosed