Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711438 | 0.96 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| Fumaric Acid SCHEMBL8711194 | 0.95 | MEN1 (0.48) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| Fumaric Acid SCHEMBL8711196 | 0.95 | MEN1 (0.48) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| SCHEMBL8711230 | 0.93 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| SCHEMBL8711324 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| SCHEMBL8711420 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| Fumaric Acid SCHEMBL9230534 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| Fumaric Acid SCHEMBL9230536 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| SCHEMBL8710993 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| SCHEMBL8712161 | 0.90 | CYP2C9 (0.58) | SMN1; SMN2LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |