Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712371 | 0.82 | TSHR (0.70) | TSHRRECQLCYP1A2CDK2HSD17B10 | |
| SCHEMBL17693470 | 0.82 | TSHR (0.52) | TSHRRECQLCYP1A2CDK2CCNB2 | |
| SCHEMBL15950878 | 0.82 | TSHR (0.66) | TSHRRECQLCYP1A2CDK2CCNB2 | |
| SCHEMBL17693471 | 0.82 | TSHR (0.52) | TSHRRECQLCYP1A2CDK2CCNB2 | |
| SCHEMBL14876945 | 0.82 | TSHR (0.66) | TSHRRECQLCYP1A2CDK2CCNB2 | |
| SCHEMBL49689 | 0.82 | TSHR (0.66) | TSHRRECQLCYP1A2CDK2CCNB2 | |
| Hydrochloric Acid SCHEMBL584648 | 0.81 | TSHR (0.64) | TSHRRECQLCYP1A2CDK2CCNB2 | |
| SCHEMBL2027216 | 0.81 | CDK2 (0.63) | TSHRRECQLCYP1A2CDK2CCNB2 | |
| Phosphoric Acid SCHEMBL3301227 | 0.80 | TSHR (0.59) | TSHRRECQLCYP1A2CDK2CCNB2 | |
| Adenine SCHEMBL9737077 | 0.75 | CDK2 (0.56) | TSHRRECQLCYP1A2CDK2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130004966-A1 | STRUCTURE OF CYTOKININS AND CYTOKININ RECEPTORS, AND MODULATION OF CYTOKININ SIGNALING | Salk Institute for Biological Studies (027731) (US) | 2013-01-03 | — | — | US | disclosed |
| EP-0540854-B1 | Preparation for promoting hair growth | SANSHO SEIYAKU KK (JP) | 1998-01-21 | — | — | EP | disclosed |