Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8712487

CCc1ccc(C)cc1.N

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.52
TP53 P04637 1/20 0.50
ACHE P22303 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TAAR1 Q96RJ0 2/20 0.48
CYP2A6 P11509 2/20 0.48
CYP1A2 P05177 1/20 0.48
AGXT P21549 2/20 0.46
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
PLK1 P53350 1/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
KCNH2 Q12809 1/20 0.43
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40574 0.97
SCHEMBL5497395 0.97 IDO1 (0.55) IDO1TP53ACHETDP1TAAR1
P-Xylene SCHEMBL28187926 0.97 IDO1 (0.55) IDO1TP53ACHETDP1TAAR1
Water SCHEMBL28807786 0.94 IDO1 (0.52) IDO1TP53ACHETDP1TAAR1
Methyl Alcohol SCHEMBL7137700 0.91 IDO1 (0.50) IDO1TP53ACHETDP1TAAR1
Ethylene SCHEMBL11370883 0.91 IDO1 (0.50) IDO1TP53ACHETDP1TAAR1
Ethyne SCHEMBL28869506 0.91 IDO1 (0.50) IDO1TP53ACHETDP1TAAR1
SCHEMBL6546215 0.88 TAAR1 (0.56) IDO1TP53ACHETDP1TAAR1
SCHEMBL6548000 0.88 IDO1 (0.48) IDO1TP53ACHETDP1TAAR1
SCHEMBL2493917 0.88 IDO1 (0.48) IDO1TP53ACHETDP1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5814669-A REACTING A PHENETHYLAMINE WITH 4-ISOPROPYL-2,5-OXAZOLIDINEDIONE; APPLYING TO PLANT, SOIL OR SEED BAYER AKTIENGESELLSCHAFT (DE) 1998-09-29 US disclosed
EP-0801083-A2 Improved functionalized resin for chemical synthesis PFIZER INC. (US) 1997-10-15 EP disclosed