Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714611 | 0.84 | HIF1A (0.36) | HIF1AALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL10535841 | 0.79 | NPSR1 (0.44) | ALDH1A1SMN1; SMN2TDP1L3MBTL1LMNA | |
| SCHEMBL10535837 | 0.79 | NPSR1 (0.44) | ALDH1A1SMN1; SMN2TDP1L3MBTL1LMNA | |
| SCHEMBL9743097 | 0.78 | KMT2A (0.38) | HIF1AALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL8503709 | 0.78 | HIF1A (0.45) | HIF1AALDH1A1L3MBTL1 | |
| SCHEMBL9742776 | 0.77 | HIF1A (0.45) | HIF1ASMN1; SMN2LMNA | |
| SCHEMBL9742771 | 0.77 | HIF1A (0.45) | HIF1ASMN1; SMN2LMNA | |
| SCHEMBL8505441 | 0.76 | HIF1A (0.41) | HIF1AALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8502333 | 0.76 | HIF1A (0.41) | HIF1AALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9895007 | 0.74 | HIF1A (0.61) | HIF1AALDH1A1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821667-A1 | NEW HYDROXIMIC ACID DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033164-A1 | NEW HYDROXIMIC ACID DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1996-10-24 | — | — | WO | disclosed |