Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7979721 | 0.98 | TAAR1 (0.59) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL13372830 | 0.85 | TAAR1 (0.80) | TAAR1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL12632170 | 0.85 | KCNH2 (0.44) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11295562 | 0.82 | TAAR1 (0.69) | TAAR1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL7969459 | 0.81 | HTR1D (0.52) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11290384 | 0.80 | TAAR1 (0.67) | TAAR1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL7983164 | 0.78 | TAAR1 (0.63) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6323409 | 0.77 | TAAR1 (0.67) | TAAR1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL177767 | 0.77 | TAAR1 (0.67) | TAAR1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL3645596 | 0.77 | TAAR1 (0.67) | TAAR1ADRA2AADRA2BADRA2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805381-A | Compositions and methods for treating and preventing neurological disorders | 优曼尼蒂治疗公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-104245696-A | Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme | KAINOS MEDICINE INC | 2014-12-24 | — | — | CN | disclosed |
| WO-1998012183-A1 | IMIDAZOLES WITH SEROTONIN RECEPTOR BINDING ACTIVITY | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1998-03-26 | — | — | WO | disclosed |