Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675855 | 0.95 | CYSLTR2 (0.40) | TSHRCYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL1668678 | 0.90 | MEN1 (0.40) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2466445 | 0.86 | MEN1 (0.42) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2947212 | 0.85 | BCHE (0.41) | TSHRCYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL30628000 | 0.84 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL177521 | 0.84 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL6328901 | 0.84 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL6336590 | 0.83 | MEN1 (0.45) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL5422365 | 0.83 | TSHR (0.48) | TSHRCYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL6327063 | 0.83 | MEN1 (0.45) | MEN1KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824799-A | A SILICON FLUORESCENT DYES FOR DETECTING ANALYTE IN IMMUNOASSAYS | BIOSITE DIAGNOSTICS INCORPORATED (US) | 1998-10-20 | — | — | US | disclosed |