Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | NEK4 | P51957 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713852 | 1.00 | HPGD (0.46) | HPGDL3MBTL1PIM1PRKACARPS6KB1 | |
| SCHEMBL8950036 | 0.90 | HSD17B10 (0.46) | HPGDL3MBTL1PIM1PRKACARPS6KB1 | |
| SCHEMBL8950032 | 0.90 | HSD17B10 (0.46) | HPGDL3MBTL1PIM1PRKACARPS6KB1 | |
| SCHEMBL20457151 | 0.83 | PIM1 (0.38) | HPGDPIM1PRKACARPS6KB1TYK2 | |
| SCHEMBL7413330 | 0.74 | BRD4 (0.48) | HPGDL3MBTL1LMNAHSD17B10MAPT | |
| SCHEMBL13268713 | 0.70 | HPGD (0.50) | HPGDL3MBTL1LMNAHSD17B10MAPT | |
| SCHEMBL7886426 | 0.70 | HPGD (0.50) | HPGDL3MBTL1LMNAHSD17B10MAPT | |
| SCHEMBL7886428 | 0.70 | HPGD (0.50) | HPGDL3MBTL1LMNAHSD17B10MAPT | |
| SCHEMBL7889670 | 0.69 | HPGD (0.49) | HPGDL3MBTL1LMNAHSD17B10MAPT | |
| SCHEMBL1265654 | 0.69 | HPGD (0.49) | HPGDL3MBTL1LMNAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817654-A | STIMULATE GROWTH HORMONES | NOVO NORDISK A/S (DK) | 1998-10-06 | — | — | US | disclosed |
| WO-1992019589-A2 | LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5140047-A | Antiinflammatory agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-18 | — | — | US | disclosed |