Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | OXTR | P30559 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713718 | 0.91 | AVPR2 (0.51) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8715453 | 0.89 | AVPR1A (0.56) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8712361 | 0.85 | AVPR1A (0.70) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8712769 | 0.81 | AVPR1A (0.55) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8712851 | 0.81 | AVPR2 (0.53) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8717790 | 0.76 | AVPR1A (0.67) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL7352855 | 0.75 | AVPR1A (0.58) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL7347200 | 0.75 | AVPR2 (0.73) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8718080 | 0.75 | AVPR1A (0.73) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8715447 | 0.74 | AVPR1A (0.53) | AVPR2AVPR1AABCB11HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |