Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.44 |
| ▸ | PARG | Q86W56 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386021 | 0.90 | HIF1A (0.54) | KDM4EAHRALDH1A1HIF1APARG | |
| SCHEMBL8713575 | 0.85 | KDM4E (0.45) | KDM4EAHRNPC1MAPTRAB9A | |
| SCHEMBL7450620 | 0.82 | KDM4E (0.50) | KDM4EAHRNPC1MAPTRAB9A | |
| SCHEMBL8714021 | 0.81 | MAPT (0.42) | KDM4EAHRNPC1MAPTRAB9A | |
| SCHEMBL758464 | 0.80 | KDM4E (0.67) | KDM4EAHRNPC1MAPTRAB9A | |
| SCHEMBL7386025 | 0.79 | MAPT (0.40) | KDM4EAHRNPC1MAPTRAB9A | |
| SCHEMBL19744161 | 0.79 | MAOB (0.67) | KDM4EMAPTRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL10443761 | 0.78 | KDM4E (0.48) | KDM4EAHRNPC1MAPTRAB9A | |
| SCHEMBL4775716 | 0.76 | KDM4E (0.71) | KDM4EAHRNPC1MAPTRAB9A | |
| SCHEMBL6981203 | 0.76 | HIF1A (0.57) | KDM4EAHRNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| CN-1131418-A | Novel fused-ring carboxylic acid compound or salt thereof, and medicinal use thereof | GREEN CROSS CORP (JP) | 1996-09-18 | — | — | CN | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |