Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 12/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714216 | 1.00 | PDE4A (0.42) | PDE4AADRB1ADRB3PDE5APDE4B | |
| SCHEMBL8714212 | 0.75 | PDE4A (0.47) | PDE4AADRB1ADRB3PDE5APDE4B | |
| SCHEMBL8714208 | 0.75 | PDE4A (0.47) | PDE4AADRB1ADRB3PDE5APDE4B | |
| SCHEMBL7148774 | 0.73 | ADRB3 (0.65) | PDE4AADRB1ADRB3 | |
| SCHEMBL7148778 | 0.73 | ADRB3 (0.65) | PDE4AADRB1ADRB3 | |
| SCHEMBL7563721 | 0.68 | PDE5A (0.50) | PDE4APDE5APDE4BPDE4DPDE4C | |
| SCHEMBL7151638 | 0.68 | PDE5A (0.43) | PDE4AADRB1ADRB3PDE5APDE4B | |
| SCHEMBL5332642 | 0.68 | PDE5A (0.57) | PDE4APDE5APDE4BPDE4DPDE4C | |
| SCHEMBL8824614 | 0.68 | KDM4E (0.49) | — | |
| SCHEMBL8824618 | 0.68 | KDM4E (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |