Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.80 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.69 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.69 |
| ▸ | CLK1 | P49759 | 1/20 | 0.69 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.69 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.69 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.69 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.69 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | MMP3 | P08254 | 2/20 | 0.66 |
| ▸ | MMP13 | P45452 | 2/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714351 | 1.00 | PIM1 (0.80) | PIM1PIM2MEN1POLBKMT2A | |
| SCHEMBL1249347 | 0.95 | PIM1 (0.71) | PIM1PIM2MEN1POLBKMT2A | |
| SCHEMBL1249348 | 0.95 | PIM1 (0.71) | PIM1PIM2MEN1POLBKMT2A | |
| SCHEMBL8310047 | 0.92 | PIM1 (0.68) | PIM1PIM2MEN1POLBKMT2A | |
| SCHEMBL13846898 | 0.91 | PIM1 (0.67) | PIM1PIM2MEN1POLBKMT2A | |
| SCHEMBL8165537 | 0.89 | MEN1 (0.84) | PIM1PIM2MEN1POLBKMT2A | |
| SCHEMBL8165534 | 0.89 | MEN1 (0.84) | PIM1PIM2MEN1POLBKMT2A | |
| SCHEMBL15816291 | 0.89 | MEN1 (0.84) | PIM1PIM2MEN1POLBKMT2A | |
| SCHEMBL2544367 | 0.89 | PIM1 (1.00) | PIM1PIM2GPR35PTGS2HRH3 | |
| SCHEMBL2544373 | 0.89 | PIM1 (1.00) | PIM1PIM2GPR35PTGS2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579770-B1 | MACROCYCLIC LACTAM PROKINETIC AGENTS | ABBOTT LAB (US) | 1996-06-26 | — | — | EP | claimed |
| US-5716975-A | NONTOXIC RHODANINE DERIVATIVES; ANTIDIABETIC AGENTS, CATHEPSIN D INHIBITORS, B-AMYLOID PROTEIN REDUCTION | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| US-5523314-A | RHODANINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-06-04 | — | — | US | disclosed |