Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720115 | 1.00 | NPC1 (0.35) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8714599 | 0.84 | KDM4E (0.32) | HPGDTYMPNOS2 | |
| SCHEMBL8714575 | 0.84 | KDM4E (0.32) | HPGDTYMPNOS2 | |
| SCHEMBL8719896 | 0.83 | TYR (0.35) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8713563 | 0.83 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8716473 | 0.83 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8713473 | 0.79 | — | — | |
| SCHEMBL8712958 | 0.79 | — | — | |
| SCHEMBL8719142 | 0.79 | — | — | |
| SCHEMBL4633204 | 0.78 | NPC1 (0.48) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726336-A | REACTING A BENZENE COMPOUND WITH A VINYLCHLOROSILANE COMPOUND IN THE PRESENCE OF A LEWIS ACID CATALYST; INTERMEDIATES FOR SILICONE POLYMERS USEFUL AS EMULSIONS, GREASES, ADHESIVES, SEALANTS, COATINGS, IN AUTOMOTIVE AND ENGINEERING FIELDS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1998-03-10 | — | — | US | disclosed |