Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289397 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2287725 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL11609820 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9210803 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7391537 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9202867 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9214895 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9211158 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2723911 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL3207026 | 1.00 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190853-A | Yellow stabilization | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-02 | — | — | US | claimed |
| US-5753730-A | Plastic lenses having a high-refractive index, process for the preparation thereof and casting polymerization process for preparing sulfur-containing urethane resin lens and lens prepared thereby | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5594088-A | PLASTICS WITH SULFIDE GROUPS, NONIONIC SURFACTANTS, SILICONE SURFACTANTS AND QUATERNARY AMMONIUM SALTS AS RELEASE AGENTS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0131020-A4 | METHOD FOR THE VOLUMETRIC DIFFERENTIATION OF LEUKOCYTES. | COULTER ELECTRONICS (US) | 1985-07-01 | — | — | EP | disclosed |
| EP-0131020-A1 | METHOD FOR THE VOLUMETRIC DIFFERENTIATION OF LEUKOCYTES. | COULTER ELECTRONICS (US) | 1985-01-16 | — | — | EP | disclosed |
| WO-1984002777-A1 | METHOD FOR THE VOLUMETRIC DIFFERENTIAL OF LEUKOCYTES | COULTER ELECTRONICS (US) | 1984-07-19 | — | — | WO | disclosed |