Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL235879 | 0.90 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL8848029 | 0.88 | — | — | |
| Dioxane SCHEMBL28241176 | 0.86 | HCAR2 (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL22263205 | 0.84 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL566318 | 0.84 | TSHR (0.34) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL9303641 | 0.82 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL28310777 | 0.82 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL28105773 | 0.82 | HCAR2 (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL27598301 | 0.81 | HCAR2 (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL5916285 | 0.80 | HCAR2 (0.37) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817633-A1 | TRANSDERMAL DEVICE FOR THE DELIVERY OF ALFUZOSIN | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-14 | — | — | EP | claimed |
| US-5614210-A | Transdermal device for the delivery of alfuzosin | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-03-25 | — | — | US | claimed |
| WO-1996030020-A1 | TRANSDERMAL DEVICE FOR THE DELIVERY OF ALFUZOSIN | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-10-03 | — | — | WO | claimed |
| EP-0817633-A1 | TRANSDERMAL DEVICE FOR THE DELIVERY OF ALFUZOSIN | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5614210-A | Transdermal device for the delivery of alfuzosin | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1996030020-A1 | TRANSDERMAL DEVICE FOR THE DELIVERY OF ALFUZOSIN | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-10-03 | — | — | WO | disclosed |