⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14041166 | 0.80 | — | — | |
| SCHEMBL9540714 | 0.77 | — | — | |
| SCHEMBL1222204 | 0.77 | CYP2D6 (0.50) | — | |
| SCHEMBL426229 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL10962239 | 0.74 | CYP2D6 (0.48) | — | |
| SCHEMBL31536491 | 0.74 | CYP2D6 (0.48) | — | |
| Hydrochloric Acid SCHEMBL9127361 | 0.74 | — | — | |
| SCHEMBL11913695 | 0.74 | — | — | |
| SCHEMBL9527331 | 0.74 | — | — | |
| SCHEMBL9938559 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002844-A1 | THIOBENZOYLATION METHOD OF PEPTIDE SEQUENCING WITH GAS CHROMATOGRAPHY AND MASS SPECTROMETRIC DETECTION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1994-02-03 | — | — | WO | claimed |
| US-5246865-A | Thiobenzoylation method of peptide sequencing with gas chromatography and mass spectrometric detection | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1993-09-21 | — | — | US | claimed |
| US-4861726-A | Method of thioacylation peptide sequencing with acylation of thiazoloinones | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-08-29 | — | — | US | claimed |
| US-20250327811-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING DITHIOESTER AND THIOCARBAMOYL AMINO ACID REACTIVE GROUPS | GLYPHIC BIOTECHNOLOGIES, INC. | 2025-10-23 | — | — | US | disclosed |
| EP-4619761-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING DITHIOESTER AND THIOCARBAMOYL AMINO ACID REACTIVE GROUPS | Glyphic Biotechnologies, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107755-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING DITHIOESTER AND THIOCARBAMOYL AMINO ACID REACTIVE GROUPS | GLYPHIC BIOTECHNOLOGIES, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| US-9221841-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150191490-A1 | MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20140018399-A1 | MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8580828-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-5246865-A | Thiobenzoylation method of peptide sequencing with gas chromatography and mass spectrometric detection | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1993-09-21 | — | — | US | disclosed |
| WO-1989008835-A1 | THIOACYLATION PEPTIDE SEQUENCING WITH ACYLATION OF THIAZOLINES | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-09-21 | — | — | WO | disclosed |
| US-4863870-A | Method of thioacylation peptide sequencing with alcoholysis of thiazolinones | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4861726-A | Method of thioacylation peptide sequencing with acylation of thiazoloinones | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-08-29 | — | — | US | disclosed |
| US-4518682-A | CONTAINING COMPOUND WHICH GIVES FOGGING EFFECT | FUJI PHOTO FILM CO., LTD. (JP) | 1985-05-21 | — | — | US | disclosed |
| US-4153416-A | Process and apparatus for pulse labelling protein material in the Edman degradation process | HEWLETT-PACKARD COMPANY, 3000 HANOVER ST., PALO ALTO, CA A CORP. OF CA | 1979-05-08 | — | — | US | disclosed |
| US-3996219-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3994889-A | 3-Heterothio derivatives of (α-thiocarbonylaminol)-7α-methoxy-cephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3962229-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1976-06-08 | — | — | US | disclosed |