⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74068 | 0.73 | — | — | |
| SCHEMBL756149 | 0.73 | — | — | |
| SCHEMBL3321786 | 0.73 | — | — | |
| SCHEMBL2384237 | 0.71 | — | — | |
| SCHEMBL7517003 | 0.71 | — | — | |
| SCHEMBL10380545 | 0.71 | — | — | |
| SCHEMBL8048278 | 0.70 | — | — | |
| SCHEMBL9224396 | 0.70 | — | — | |
| SCHEMBL1314466 | 0.70 | — | — | |
| SCHEMBL11253831 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827925-A | POLYMERIC MATERIAL BONDED TO DRUG THROUGH PH-SENSITIVE CLEAVABLE COVALENT BOND | MONSANTO COMPANY (US) | 1998-10-27 | — | — | US | claimed |
| EP-0540580-B1 | POLYMERIC DRUG DELIVERY SYSTEM | SEARLE & CO (US) | 1994-04-13 | — | — | EP | claimed |
| EP-0540580-A1 | POLYMERIC DRUG DELIVERY SYSTEM. | SEARLE & CO (US) | 1993-05-12 | — | — | EP | claimed |
| WO-1992001477-A1 | POLYMERIC DRUG DELIVERY SYSTEM | G.D. SEARLE & CO. (US) | 1992-02-06 | — | — | WO | claimed |
| US-5827925-A | POLYMERIC MATERIAL BONDED TO DRUG THROUGH PH-SENSITIVE CLEAVABLE COVALENT BOND | MONSANTO COMPANY (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0540580-B1 | POLYMERIC DRUG DELIVERY SYSTEM | SEARLE & CO (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0540580-A1 | POLYMERIC DRUG DELIVERY SYSTEM. | SEARLE & CO (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001477-A1 | POLYMERIC DRUG DELIVERY SYSTEM | G.D. SEARLE & CO. (US) | 1992-02-06 | — | — | WO | disclosed |