SCHEMBL871612

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL871613	1.00	PDE4B (0.42)	PDE4BNPC1RAB9ACNR1CNR2
	SCHEMBL870899	0.91	PDE4B (0.47)	PDE4BNPC1RAB9ACNR1GPR55
	SCHEMBL870898	0.91	PDE4B (0.47)	PDE4BNPC1RAB9ACNR1GPR55
	SCHEMBL3032493	0.89	PDE4B (0.44)	PDE4BKDM4ESMN1; SMN2HSD17B10DGAT1
	SCHEMBL3032496	0.89	PDE4B (0.44)	PDE4BKDM4ESMN1; SMN2HSD17B10DGAT1
	SCHEMBL870872	0.89	PDE4B (0.43)	PDE4BNPC1RAB9AKDM4ESMN1; SMN2
	SCHEMBL870871	0.89	PDE4B (0.43)	PDE4BNPC1RAB9AKDM4ESMN1; SMN2
	SCHEMBL3023366	0.89	PDE4B (0.47)	PDE4BCNR2DGAT1EGLN1
	SCHEMBL3023362	0.89	PDE4B (0.47)	PDE4BCNR2DGAT1EGLN1
	SCHEMBL870787	0.88	PDE4B (0.46)	PDE4BNPC1RAB9AHPGDSEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.